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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL479804
Molecular formula	C8H14N2O5
IUPAC name	(2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioic acid
Molecular weight	218.209
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-3.3
Synonyms	BDBM50252050 ZINC40933343 (2S,4R)-4-(3-Amino-3-oxopropyl)glutamic acid (2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioic acid
Inchi Key	BFKOJIBMYJQCOV-UHNVWZDZSA-N
Inchi ID	InChI=1S/C8H14N2O5/c9-5(8(14)15)3-4(7(12)13)1-2-6(10)11/h4-5H,1-3,9H2,(H2,10,11)(H,12,13)(H,14,15)/t4-,5+/m1/s1
PubChem CID	24905646
ChEMBL	CHEMBL479804
IUPHAR	N/A
BindingDB	50252050
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22399	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
22394	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
557966	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
22398	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
22395	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
522217	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
22396	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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