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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3957222
Molecular formula	C28H28N2O3
IUPAC name	6,18-dimethoxy-19-phenylmethoxy-10,13-diazapentacyclo[11.8.0.03,11.04,9.016,21]henicosa-3(11),4(9),5,7,16,18,20-heptaene
Molecular weight	440.543
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.9
Synonyms	BDBM50195264 SCHEMBL19427751
Inchi Key	BBCCPQCCAUUIFQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H28N2O3/c1-31-20-8-9-24-22(13-20)23-14-26-21-15-28(33-17-18-6-4-3-5-7-18)27(32-2)12-19(21)10-11-30(26)16-25(23)29-24/h3-9,12-13,15,26,29H,10-11,14,16-17H2,1-2H3
PubChem CID	131978695
ChEMBL	CHEMBL3957222
IUPHAR	N/A
BindingDB	50195264
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536471	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
536470	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
536472	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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