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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2031471
Molecular formula	C23H31N3O2
IUPAC name	8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-2-propan-2-yl-5,6-dihydrobenzo[h]cinnolin-3-one
Molecular weight	381.52
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50384402
Inchi Key	AZBGZTWRYFLSNW-QGZVFWFLSA-N
Inchi ID	InChI=1S/C23H31N3O2/c1-16(2)26-22(27)15-19-8-7-18-14-20(9-10-21(18)23(19)24-26)28-13-5-12-25-11-4-6-17(25)3/h9-10,14-17H,4-8,11-13H2,1-3H3/t17-/m1/s1
PubChem CID	70690039
ChEMBL	CHEMBL2031471
IUPHAR	N/A
BindingDB	50384402
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17988	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
17986	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
17987	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
17990	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
17989	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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