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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL98168
Molecular formula	C25H25NO2
IUPAC name	1'-(2-naphthalen-1-ylethyl)spiro[4H-isochromene-3,4'-piperidine]-1-one
Molecular weight	371.48
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.4
Synonyms	BDBM50074003 1''-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isochromene-3,4''-(hexahydropyridine)]-1-one
Inchi Key	AROUGQIPMYQUEE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25NO2/c27-24-23-11-4-2-7-21(23)18-25(28-24)13-16-26(17-14-25)15-12-20-9-5-8-19-6-1-3-10-22(19)20/h1-11H,12-18H2
PubChem CID	44330880
ChEMBL	CHEMBL98168
IUPHAR	N/A
BindingDB	50074003
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12637	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
12638	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
12636	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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