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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	H-Tyr-D-Ala-Gly-Phe-Met-NH2
Molecular formula	C28H38N6O6S
IUPAC name	(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide
Molecular weight	586.708
Hydrogen bond acceptor	8
Hydrogen bond donor	7
XlogP	-0.1
Synonyms	(S)-2-((S)-2-(2-((R)-2-((S)-2-Amino-3-(4-hydroxyphenyl)Propanamido)Propanamido)acetamido)-3-phenylPropanamido)-4-(methylthio)butanamide D-Ala2-Met-Enkephalinamide AKOS030525633 Tyr-D-Ala-Gly-Phe-Met-NH2 [d-Ala2,met5]-enkephalinamide BDBM50304493 Tyr-DAla-Gly-Phe-Met-NH2 (D-Ala2,Met5)enkephalin amide CHEMBL595972 61090-95-7 LY-127623 C-54711 ZINC49757425 [ Show all ]
Inchi Key	ANZXICRKKYOVMY-SZOBAZRNSA-N
Inchi ID	InChI=1S/C28H38N6O6S/c1-17(32-27(39)21(29)14-19-8-10-20(35)11-9-19)26(38)31-16-24(36)33-23(15-18-6-4-3-5-7-18)28(40)34-22(25(30)37)12-13-41-2/h3-11,17,21-23,35H,12-16,29H2,1-2H3,(H2,30,37)(H,31,38)(H,32,39)(H,33,36)(H,34,40)/t17-,21+,22+,23+/m1/s1
PubChem CID	10371120
ChEMBL	CHEMBL595972
IUPHAR	N/A
BindingDB	50304493
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10056	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
10057	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
10054	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
10055	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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