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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3344465
Molecular formula	C21H25NO2S
IUPAC name	(1S)-14-(cyclobutylmethyl)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
Molecular weight	355.496
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.6
Synonyms	BDBM50030486 SCHEMBL16564399
Inchi Key	ALDCLQHVTZPMQV-SFHVURJKSA-N
Inchi ID	InChI=1S/C21H25NO2S/c1-24-20-9-14-5-6-22-12-15-8-16(7-13-3-2-4-13)25-21(15)11-18(22)17(14)10-19(20)23/h8-10,13,18,23H,2-7,11-12H2,1H3/t18-/m0/s1
PubChem CID	72699718
ChEMBL	CHEMBL3344465
IUPHAR	N/A
BindingDB	50030486
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442036	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
442035	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
442038	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
442037	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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