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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1767144
Molecular formula	C22H23N3O3
IUPAC name	4-[[3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-oxophthalazin-1-yl]methyl]benzoic acid
Molecular weight	377.444
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	0.6
Synonyms	BDBM50418273
Inchi Key	AIQKTJZHRRQKTE-QGZVFWFLSA-N
Inchi ID	InChI=1S/C22H23N3O3/c1-24-12-4-5-17(24)14-25-21(26)19-7-3-2-6-18(19)20(23-25)13-15-8-10-16(11-9-15)22(27)28/h2-3,6-11,17H,4-5,12-14H2,1H3,(H,27,28)/t17-/m1/s1
PubChem CID	52937634
ChEMBL	CHEMBL1767144
IUPHAR	N/A
BindingDB	50418273
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6455	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
6456	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
6458	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
6457	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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