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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Indolo[2,3-b]quinoxalin-6-yl-acetic acid ethyl ester
Molecular formula	C18H15N3O2
IUPAC name	ethyl 2-indolo[3,2-b]quinoxalin-6-ylacetate
Molecular weight	305.337
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	ethyl 2-indolo[3,2-b]quinoxalin-6-ylethanoate Oprea1_306545 BDBM48903 HMS608P02 SR-01000467024 25681-03-2 CHEMBL1539939 ethyl 2-indolo[2,3-b]quinoxalin-5-ylacetate MLS000035955 STL301016 AKOS000528190 ethyl 6H-indolo[2,3-b]quinoxalin-6-ylacetate Oprea1_645071 2-(6-indolo[3,2-b]quinoxalinyl)acetic acid ethyl ester CCG-109349 SR-01000467024-1 ChemDiv1_007724 ethyl 2-indolo[3,2-b]quinoxalin-6-ylacetate MolPort-000-678-275 ZINC358278 BAS 00033013 HMS2369P19 SMR000001010 2-indolo[3,2-b]quinoxalin-6-ylacetic acid ethyl ester cid_645300 MCULE-1164662736 ST50332400 AC1LDB67 [ Show all ]
Inchi Key	AHABQJDNQDDOMO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H15N3O2/c1-2-23-16(22)11-21-15-10-6-3-7-12(15)17-18(21)20-14-9-5-4-8-13(14)19-17/h3-10H,2,11H2,1H3
PubChem CID	645300
ChEMBL	CHEMBL1539939
IUPHAR	N/A
BindingDB	48903
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5379	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
5380	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
5381	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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