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Name | C3a anaphylatoxin chemotactic receptor |
---|---|
Species | Homo sapiens (Human) |
Gene | C3AR1 |
Synonym | C3a anaphylatoxin chemotactic receptor C3a receptor C3AR anaphylatoxin C3a receptor complement component 3a receptor 1 [ Show all ] |
Disease | N/A |
Length | 482 |
Amino acid sequence | MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNSTTV |
UniProt | Q16581 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q16581 |
3D structure model | This predicted structure model is from GPCR-EXP Q16581. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4761 |
IUPHAR | 31 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
651 | CHEMBL1170635 | C38H54N10O7 | 762.913 | 9 / 10 | -1.6 | No |
521471 | CHEMBL3736483 | C25H32N6O6 | 512.567 | 8 / 5 | 2.4 | No |
4721 | CHEMBL228582 | C18H21ClN4O4 | 392.84 | 5 / 4 | 2.0 | Yes |
521613 | CHEMBL3736513 | C22H30BrN7O5 | 552.43 | 8 / 5 | 1.3 | No |
6391 | CHEMBL228847 | C19H21ClN4O3 | 388.852 | 4 / 4 | 2.3 | Yes |
15073 | CHEMBL234100 | C27H32ClN3O2 | 466.022 | 3 / 1 | 4.7 | Yes |
442412 | CHEMBL3342685 | C23H25N5O4 | 435.484 | 6 / 4 | 2.2 | Yes |
19928 | CHEMBL228635 | C23H22N4O5 | 434.452 | 6 / 4 | 2.8 | Yes |
24022 | CHEMBL1170650 | C34H58N10O7 | 718.901 | 9 / 10 | -0.2 | No |
25524 | CHEMBL229005 | C24H24F2N4O4 | 470.477 | 7 / 4 | 3.0 | Yes |
26804 | CHEMBL1170639 | C32H53N9O7 | 675.832 | 9 / 9 | -2.1 | No |
27418 | CHEMBL387686 | C17H18Cl2N4O4 | 413.255 | 5 / 4 | 2.3 | Yes |
522511 | CHEMBL3734765 | C29H34N6O5 | 546.628 | 7 / 5 | 2.6 | No |
40086 | CHEMBL234523 | C27H33N3O2 | 431.58 | 3 / 1 | 5.0 | Yes |
41520 | CHEMBL232029 | C28H37N3O2 | 447.623 | 3 / 1 | 5.1 | No |
43841 | CHEMBL396031 | C27H34FN3O2 | 451.586 | 4 / 1 | 5.2 | No |
48132 | CHEMBL233232 | C28H35N3O2 | 445.607 | 3 / 1 | 5.0 | Yes |
522979 | CHEMBL3735746 | C24H34N6O7 | 518.571 | 9 / 5 | 1.2 | No |
53228 | CHEMBL231405 | C17H19ClN4O4 | 378.813 | 5 / 4 | 1.7 | Yes |
53644 | CHEMBL1170025 | C76H123N17O20S2 | 1659.04 | 24 / 21 | 0.3 | No |
443887 | CHEMBL3342683 | C29H29N5O4 | 511.582 | 6 / 4 | 3.8 | No |
74381 | CHEMBL265866 | C17H18ClFN4O4 | 396.803 | 6 / 4 | 1.8 | Yes |
523750 | CHEMBL3736489 | C28H42N6O5 | 542.681 | 7 / 5 | 3.4 | No |
76848 | CHEMBL396262 | C28H35FN2O2 | 450.598 | 3 / 1 | 6.0 | No |
80472 | CHEMBL234731 | C28H33FN2O2 | 448.582 | 3 / 1 | 6.1 | No |
86020 | CHEMBL1170229 | C43H63N11O7 | 846.047 | 10 / 10 | -1.1 | No |
524026 | CHEMBL3735774 | C23H32N6O7S | 536.604 | 9 / 5 | 1.2 | No |
90740 | CHEMBL94579 | C27H29N3O | 411.549 | 3 / 1 | 5.6 | No |
524412 | CHEMBL3734890 | C25H36N6O6 | 516.599 | 8 / 5 | 1.6 | No |
100407 | CHEMBL96477 | C19H20ClN3 | 325.84 | 2 / 1 | 4.3 | Yes |
103654 | CHEMBL313866 | C24H21Cl2N3 | 422.353 | 2 / 1 | 6.1 | No |
120042 | CHEMBL387755 | C24H24Cl2N4O4 | 503.38 | 5 / 4 | 4.1 | No |
121212 | CHEMBL1172879 | C35H57N9O7 | 715.897 | 9 / 8 | -2.4 | No |
525200 | CHEMBL3736115 | C24H34N6O6 | 502.572 | 8 / 5 | 1.6 | No |
127999 | CHEMBL1170648 | C36H59N9O8 | 745.923 | 10 / 9 | -3.1 | No |
525229 | CHEMBL3736337 | C24H31F3N6O5 | 540.544 | 10 / 5 | 2.6 | No |
525256 | CHEMBL3735240 | C29H38N6O6 | 566.659 | 8 / 5 | 3.0 | No |
129779 | CHEMBL233028 | C27H33F2N3O2 | 469.577 | 5 / 1 | 4.2 | Yes |
129783 | CHEMBL97335 | C24H21Cl2N3 | 422.353 | 2 / 1 | 6.1 | No |
130053 | CID 70694925 | C95H145N31O21 | 2057.4 | 26 / 35 | -4.2 | No |
525296 | CHEMBL3736340 | C26H38N6O7 | 546.625 | 9 / 5 | 1.6 | No |
131809 | CHEMBL234522 | C27H34FN3O2 | 451.586 | 4 / 1 | 5.2 | No |
525349 | CHEMBL3736020 | C26H36N6O5 | 512.611 | 7 / 5 | 2.2 | No |
133629 | CHEMBL319332 | C24H23N3 | 353.469 | 2 / 1 | 5.0 | Yes |
134530 | CHEMBL1170349 | C34H58N12O8 | 762.914 | 11 / 12 | -5.2 | No |
135651 | CHEMBL97420 | C26H25Cl2N3 | 450.407 | 2 / 1 | 6.8 | No |
136286 | CHEMBL1170035 | C35H58N10O7 | 730.912 | 10 / 9 | -4.0 | No |
137496 | CHEMBL390834 | C17H19ClN4O3S | 394.874 | 5 / 4 | 2.3 | Yes |
525510 | CHEMBL3735507 | C21H28BrN7O5 | 538.403 | 8 / 5 | 0.9 | No |
142679 | CHEMBL228900 | C24H32N6O3 | 452.559 | 5 / 4 | -0.9 | Yes |
525673 | CHEMBL3735993 | C25H33N7O5 | 511.583 | 7 / 6 | 1.3 | No |
145719 | CHEMBL2021602 | C35H59N9O7 | 717.913 | 9 / 9 | -1.5 | No |
525760 | CHEMBL3735568 | C25H32N6O5S | 528.628 | 8 / 5 | 3.0 | No |
149636 | CID 49799040 | C86H128N22O21 | 1806.1 | 24 / 26 | -4.5 | No |
149851 | CHEMBL234521 | C28H37N3O3 | 463.622 | 4 / 1 | 5.1 | No |
152771 | CHEMBL1170044 | C34H54N10O8 | 730.868 | 10 / 9 | -4.9 | No |
158937 | CHEMBL1170232 | C36H59N9O9 | 761.922 | 10 / 10 | 0.7 | No |
163967 | CHEMBL1170438 | C37H52N10O7 | 748.886 | 9 / 10 | -1.4 | No |
164264 | CHEMBL1170045 | C39H57N9O7 | 763.941 | 9 / 8 | -1.8 | No |
166549 | BDBM50388997 | C90H140N30O20 | 1962.3 | 25 / 30 | -6.1 | No |
168855 | CHEMBL396030 | C27H32F3N3O2 | 487.567 | 6 / 1 | 5.1 | No |
169179 | CHEMBL1170026 | C58H90N14O13S | 1223.5 | 17 / 13 | -2.2 | No |
175880 | CHEMBL230034 | C24H26N4O4 | 434.496 | 5 / 4 | 2.8 | Yes |
177389 | CHEMBL228846 | C19H21ClN4O3 | 388.852 | 4 / 4 | 2.3 | Yes |
177506 | CHEMBL1170046 | C40H56N10O7 | 788.951 | 9 / 9 | -0.9 | No |
179027 | CHEMBL319113 | C23H20F2N4 | 390.438 | 5 / 1 | 4.0 | Yes |
180703 | CHEMBL1170220 | C42H57N9O7 | 799.974 | 9 / 8 | 0.6 | No |
184110 | CHEMBL1170223 | C35H58N10O7 | 730.912 | 10 / 9 | -3.9 | No |
526798 | CHEMBL3736239 | C20H34N6O6 | 454.528 | 8 / 5 | 1.0 | Yes |
186775 | CHEMBL229006 | C24H24Cl2N4O4 | 503.38 | 5 / 4 | 4.1 | No |
187703 | CHEMBL96138 | C26H26N4O | 410.521 | 3 / 2 | 4.2 | Yes |
526893 | CHEMBL3734935 | C22H38N6O5 | 466.583 | 7 / 5 | 1.7 | Yes |
190553 | CID 70684422 | C92H139N31O20 | 1999.32 | 25 / 34 | -4.3 | No |
527081 | CHEMBL3735614 | C22H27N3O5 | 413.474 | 5 / 4 | 1.9 | Yes |
195426 | CHEMBL409773 | C27H25Cl2N3O3 | 510.415 | 4 / 1 | 4.6 | No |
527279 | CHEMBL3735180 | C26H38N6O7 | 546.625 | 9 / 5 | 1.6 | No |
203013 | CHEMBL234005 | C25H33N3O2S | 439.618 | 4 / 1 | 4.5 | Yes |
205123 | CHEMBL388204 | C28H37N3O2 | 447.623 | 3 / 1 | 5.1 | No |
207639 | CHEMBL1170643 | C34H57N9O8 | 719.885 | 10 / 10 | -2.6 | No |
210230 | CHEMBL232418 | C27H27Cl2N3O2 | 496.432 | 3 / 1 | 5.0 | Yes |
527556 | CHEMBL3735495 | C25H36N6O6 | 516.599 | 8 / 5 | 1.6 | No |
210785 | BDBM50388998 | C88H136N26O19 | 1862.22 | 24 / 27 | -3.9 | No |
527604 | CHEMBL3736325 | C29H36N6O6 | 564.643 | 8 / 5 | 3.2 | No |
527634 | CHEMBL3735332 | C26H38N6O6 | 530.626 | 8 / 5 | 1.9 | No |
527667 | CHEMBL3735764 | C28H34N6O6 | 550.616 | 8 / 5 | 2.8 | No |
215618 | CHEMBL233675 | C27H34ClN3O2 | 468.038 | 3 / 1 | 5.4 | No |
527861 | CHEMBL3734951 | C24H35N7O5 | 501.588 | 7 / 6 | 1.3 | No |
527868 | CHEMBL3735048 | C25H31N7O5 | 509.567 | 8 / 5 | 1.9 | No |
527923 | CHEMBL3736432 | C24H35N7O5 | 501.588 | 7 / 6 | 1.8 | No |
527980 | CHEMBL3735664 | C22H31N7O5 | 473.534 | 8 / 5 | 0.6 | Yes |
226514 | CHEMBL394538 | C18H22N4O5 | 374.397 | 6 / 4 | 1.0 | Yes |
226665 | CID 70682339 | C91H139N31O19 | 1971.31 | 24 / 34 | -4.5 | No |
230464 | CHEMBL1170636 | C38H54N10O8 | 778.912 | 10 / 11 | -2.7 | No |
528198 | CHEMBL3736195 | C24H35N7O5 | 501.588 | 8 / 5 | 1.4 | No |
236881 | CHEMBL1170638 | C34H57N9O8 | 719.885 | 10 / 10 | -2.7 | No |
250944 | CHEMBL228901 | C26H28N4O3 | 444.535 | 4 / 4 | 3.4 | Yes |
251229 | CHEMBL3342676 | C22H28N4O3S | 428.551 | 5 / 4 | 2.4 | Yes |
253297 | BDBM50389005 | C94H143N31O21 | 2043.37 | 26 / 31 | -6.0 | No |
254292 | CID 70686567 | C90H139N31O18 | 1943.3 | 24 / 34 | -4.3 | No |
451838 | CHEMBL3342690 | C25H30N6O3 | 462.554 | 5 / 4 | 2.2 | Yes |
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