Detailed GPCR-I-TASSER Statistics for Q16581

Submitted Sequence

>sp|Q16581|C3AR_HUMAN
MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIW
FLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDR
CLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSS
SLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSAD
SLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSA
SSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIV
FRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVC
IALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNST
TV

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |  
Sequence MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNSTTV
Prediction CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCSSSSSSHHHHHHHHHHHHHHHHHHSSSSSCCCSSSSCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCSSSSSHHHHHHHHHHCCCCSSHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSHHHCCCCCHHHSSSHHHHHHHHHHHCCHHHHHSSSSSCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 99888898877887776322589999999999999998878986787664245568899999999999999998799999998468988867689999999999999999999999998788872705432577741123310899999999996999852589758903883578876655245433233121023321002220100231067777776540440000025653211336631244317888999999999985357467528616533324234128999999997512757024674267630236777885323168999999999999999999999999999999984544644123677889999999999630999999999853787278999999999999999999999999992599899999999998702423566677887888888787878889

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |  
Sequence MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNSTTV
Prediction 44323343131323334243000000010002001202320010000000233110000000000100000000000100000243201001000100000112011000000000000000000000202321121000000000011000001000000202537432200010223122323322222221212222222012010000000000000000000001024221210100010000000100100000000000000000000212122310100000000000000000000000223653211000010126332310100011110120120122110011001012223254433331000000000000100021100000000002241312300100000010000200010000000004600410140022004300344354445344444345445446

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |  
Sec.Str
Seq		CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCSSSSSSHHHHHHHHHHHHHHHHHHSSSSSCCCSSSSCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCSSSSSHHHHHHHHHHCCCCSSHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSHHHCCCCCHHHSSSHHHHHHHHHHHCCHHHHHSSSSSCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNSTTV
15nddA 0.18 0.20 0.84 2.10Download AYIYEFFSVDEFSASVLTGKLTTVFLPIVYTIVFVVALPSNGMALWVFLFRTKKAPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYANMYCSILFLTCLSVQRAWEIVNPMGHSR-KKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPQITTCHDVLPEQL-------LVGDMFNYFLSLA------IGVFLFPAFLTASAYVLMIRALADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLA---NEGK--------------------------VKEAQAAAEQLKTTRNAYIQKYLENSE--KKRKRAIKLAVTVAAMYLICFTPSNLLLVVHYFL-IKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNAL--------------------------------
24mbsA 0.24 0.18 0.60 4.12Download -----------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILIYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAA--AQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFP----------------------------------------------------------------------------------------------------------------------------------------------------YSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMEEEKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQENNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ-------------------------------
34n6hA 0.31 0.22 0.61 2.70Download ----------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKKTATNIYIFNLALADALATSTLPFQSAKYLME-TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQ---------------------------------------------------------------------------------------------------------------------------------------------------FPSPS--WYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDID-RRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------------
44ib4 0.22 0.20 0.59 1.53Download ----------------EEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKQYATNYFLMSLAVADLLVGFVMPIALLTIMFEAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIPVPIKGIET-NPNNITCVLTKE----------------------------------------------------------------------------------------------------------------------------------------------------------RFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAAISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCN--QTTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR---------------------------
55t1a 0.18 0.20 0.80 1.15Download -----------------VKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKLKCLTDIYLLNLAISDLLFLITLPLWAHSAA--NEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKQKE-DSVYVCGPYFPRG----WNN-------------FHTIMRNILGLVLPLLIMVICYSGISRASKSRINIFIDEGLRLKIYKDTSPSLNAAKSE------LDKAIGR----NTNGVITKDEAKLFNQDVDAA----V-R-------GILRNAK-LKPVYDSLDA--VRRAALINMVFQMGETNSLRMLALATPNRATTFRTYPPPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF--------------------------------
65t1aA 0.16 0.20 0.87 2.99Download ------------------KQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKKCLTDIYLLNLAISDLLFLITLPLWAHSAAN--EWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKQKED-SVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGISRASKSRINIFEMLRIDEGLRLKIYKDSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMG------ETGVAGFTNSLRMLQQKR--WDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYPPPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF--------------------------------
74djh 0.27 0.25 0.39 1.71Download -------------------PAIPVIITAVYSVVFVVGLVGNSLVMFVIIYTKMKTATNIYIFNLALADALVTTTMPFQSTV-YLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVRVDVIECSLQFPDDDYSFIFAFVIPVLIIIVCYTLMILRLKS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84mbsA 0.24 0.19 0.60 4.02Download -----------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRKSMTDIYLLNLAISDLFFLLTVPFWAHYAAA--QWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHF----------------------------------------------------------------------------------------------------------------------------------------------------PYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRE---KKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ-------------------------------
95o9hA 0.37 0.25 0.61 2.46Download ----------------NTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLACLALPALFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPAWCQRFRGAGLAWILCAVAWGLALLLTIPSALYRVVREEPPKVLCGVDHD--------------------------------------------------------------------------------------------------------------------------------------------------------KRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSAR-ETRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQKSLPELLREVLTEESVVR---------------------
105o9hA 0.38 0.25 0.61 3.12Download ----------------NTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLACLALPALFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPAWCQRFRGAGLAWILCAVAWGLALLLTIPSALYRVVREEPPKVLCGVDHD--------------------------------------------------------------------------------------------------------------------------------------------------------KRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSARE-TRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQKSLPELLREVL----TEESVVR-----------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-1.99 (Read more about C-score)
  • Estimated TM-score = 0.48±0.15
  • Estimated RMSD = 12.0±4.4Å

  • Download Model 2
  • C-score = -2.70

  • Download Model 3
  • C-score = -3.22

  • Download Model 4
  • C-score = -3.49

  • Download Model 5
  • C-score = -3.66


    • [Click on Q16581_results.tar.bz2 to download the tarball file including all modeling results listed on this page]