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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C3a anaphylatoxin chemotactic receptor
Species	Homo sapiens (Human)
Gene	C3AR1
Synonym	C3a anaphylatoxin chemotactic receptor C3a receptor C3AR anaphylatoxin C3a receptor complement component 3a receptor 1 C3a-R [ Show all ]
Disease	N/A
Length	482
Amino acid sequence	MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNSTTV
UniProt	Q16581
Protein Data Bank	N/A
GPCR-HGmod model	Q16581
3D structure model	This predicted structure model is from GPCR-EXP Q16581.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4761
IUPHAR	31
DrugBank	N/A

Ligand

Name	CHEMBL396262
Molecular formula	C28H35FN2O2
IUPAC name	2-cyclohexyl-N-[1-[3-(2-fluorophenyl)propanoyl]piperidin-4-yl]-2-phenylacetamide
Molecular weight	450.598
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.0
Synonyms	BDBM50423080
Inchi Key	FFBSHMPPTOAKJD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H35FN2O2/c29-25-14-8-7-9-21(25)15-16-26(32)31-19-17-24(18-20-31)30-28(33)27(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1,3-4,7-11,14,23-24,27H,2,5-6,12-13,15-20H2,(H,30,33)
PubChem CID	44430558
ChEMBL	CHEMBL396262
IUPHAR	N/A
BindingDB	50423080
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1995.0 nM	PMID17459702	BindingDB
IC50	1995.26 nM	PMID17459702	ChEMBL

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