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Name | C3a anaphylatoxin chemotactic receptor |
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Species | Homo sapiens (Human) |
Gene | C3AR1 |
Synonym | C3a anaphylatoxin chemotactic receptor C3a receptor C3AR anaphylatoxin C3a receptor complement component 3a receptor 1 [ Show all ] |
Disease | N/A |
Length | 482 |
Amino acid sequence | MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNSTTV |
UniProt | Q16581 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q16581 |
3D structure model | This predicted structure model is from GPCR-EXP Q16581. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4761 |
IUPHAR | 31 |
DrugBank | N/A |
Name | CHEMBL3736115 |
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Molecular formula | C24H34N6O6 |
IUPAC name | (2S)-5-(diaminomethylideneamino)-2-[[2-[(1S)-1-[(3-methoxybenzoyl)amino]-3-methylbutyl]-5-methyl-1,3-oxazole-4-carbonyl]amino]pentanoic acid |
Molecular weight | 502.572 |
Hydrogen bond acceptor | 8 |
Hydrogen bond donor | 5 |
XlogP | 1.6 |
Synonyms | SCHEMBL14952353 |
Inchi Key | HXXFRBRLJLGXNV-ROUUACIJSA-N |
Inchi ID | InChI=1S/C24H34N6O6/c1-13(2)11-18(29-20(31)15-7-5-8-16(12-15)35-4)22-30-19(14(3)36-22)21(32)28-17(23(33)34)9-6-10-27-24(25)26/h5,7-8,12-13,17-18H,6,9-11H2,1-4H3,(H,28,32)(H,29,31)(H,33,34)(H4,25,26,27)/t17-,18-/m0/s1 |
PubChem CID | 89570460 |
ChEMBL | CHEMBL3736115 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Inhibition | 134.0 % | PMID26522948 | ChEMBL |
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