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Name | 5-hydroxytryptamine receptor 2A |
---|---|
Species | Canis lupus familiaris (Dog) |
Gene | HTR2A |
Synonym | 5-HT-2 5-HT-2A 5-hydroxytryptamine receptor Serotonin receptor 2A |
Disease | N/A for non-human GPCRs |
Length | 470 |
Amino acid sequence | MDVLFEDNAPLSPTTSSLMPSNGDPRLYGNDLNAGDANTSDAFNWTVDAENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDIIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKKDAKSTDNDYSMVALGKQHSEDAPTDNINTVNEKVSCV |
UniProt | O46635 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5781 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
14445 | CHEMBL3286560 | C16H19N3O | 269.348 | 4 / 1 | 2.4 | Yes |
28508 | CHEMBL576631 | C17H19N5 | 293.374 | 4 / 1 | 2.8 | Yes |
54734 | 2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine | C15H17N3 | 239.322 | 3 / 1 | 2.1 | Yes |
277623 | CHEMBL565547 | C17H19N5 | 293.374 | 4 / 1 | 2.4 | Yes |
286881 | CHEMBL1214946 | C17H18ClFN4O2 | 364.805 | 5 / 0 | 2.0 | Yes |
355717 | CHEMBL3286561 | C16H20N4 | 268.364 | 4 / 2 | 2.4 | Yes |
438323 | CHEMBL492301 | C21H25ClN2O3S | 420.952 | 5 / 1 | 3.8 | Yes |
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