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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1214946
Molecular formula	C17H18ClFN4O2
IUPAC name	2-[4-(4-chloro-1-methylpyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Molecular weight	364.805
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.0
Synonyms	BDBM50324542 SCHEMBL3136020 2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Inchi Key	QUDDUNFBOHGRTM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18ClFN4O2/c1-21-10-14(18)16(20-21)17(25)23-8-6-22(7-9-23)11-15(24)12-2-4-13(19)5-3-12/h2-5,10H,6-9,11H2,1H3
PubChem CID	24810867
ChEMBL	CHEMBL1214946
IUPHAR	N/A
BindingDB	50324542
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
286879	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
286881	5-hydroxytryptamine receptor 2A	O46635	HTR2A	Canis lupus familiaris (Dog)	470
286882	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
543749	5-hydroxytryptamine receptor 2A	P50128	HTR2A	Macaca mulatta (Rhesus macaque)	471
286880	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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