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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL374869
Molecular formula	C27H32N2O5
IUPAC name	2-[2-[4-[1-[2-(1,3-dioxolan-2-yl)ethyl]indol-3-yl]piperidin-1-yl]ethoxy]benzoic acid
Molecular weight	464.562
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.4
Synonyms	ZUAMSTWVTDGQIR-UHFFFAOYSA-N 2-(2-{4-[1-(2-[1,3]dioxolan-2-yl-ethyl)-1H-indol-3-yl]-piperidin-1-yl}-ethoxy)-benzoic acid BDBM50156870 SCHEMBL5349798 2-(2-{4-[1-(2-[1,3]dioxolan-2-yl-ethyl)-1H-indol-3-yl]piperidin-1-yl}ethoxy)benzoic acid
Inchi Key	ZUAMSTWVTDGQIR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32N2O5/c30-27(31)22-6-2-4-8-25(22)32-16-15-28-12-9-20(10-13-28)23-19-29(14-11-26-33-17-18-34-26)24-7-3-1-5-21(23)24/h1-8,19-20,26H,9-18H2,(H,30,31)
PubChem CID	10161929
ChEMBL	CHEMBL374869
IUPHAR	N/A
BindingDB	50156870
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
437440	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
437441	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
437439	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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