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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1773278
Molecular formula	C23H30N6O4S
IUPAC name	tert-butyl 4-[[[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]methyl]piperidine-1-carboxylate
Molecular weight	486.591
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.0
Synonyms	142895-EP2292620A2 BDBM50343437 142895-EP2287165A2 SCHEMBL388000 4-{[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester 142895-EP2287166A2 tert-butyl 4-((1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)methyl)piperidine-1-carboxylate [ Show all ]
Inchi Key	ZLEVVZJCRQACCT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H30N6O4S/c1-23(2,3)33-22(30)28-11-9-16(10-12-28)13-24-20-19-14-27-29(21(19)26-15-25-20)17-5-7-18(8-6-17)34(4,31)32/h5-8,14-16H,9-13H2,1-4H3,(H,24,25,26)
PubChem CID	53630396
ChEMBL	CHEMBL1773278
IUPHAR	N/A
BindingDB	50343437
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
431264	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
431265	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468

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