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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL376202
Molecular formula	C27H28N2O3S
IUPAC name	2-methoxy-5-[[4-[1-(thiophen-2-ylmethyl)indol-3-yl]piperidin-1-yl]methyl]benzoic acid
Molecular weight	460.592
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.6
Synonyms	BDBM50156872 SCHEMBL5344198 2-methoxy-5-[4-(1-thiophen-2-ylmethyl-1H-indol-3-yl)-piperidin-1-ylmethyl]benzoic acid ZERWJGDOIKPLKM-UHFFFAOYSA-N 2-methoxy-5-[4-(1-thiophen-2-ylmethyl-1H-indol-3-yl)-piperidin-1-ylmethyl]-benzoic Acid
Inchi Key	ZERWJGDOIKPLKM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28N2O3S/c1-32-26-9-8-19(15-23(26)27(30)31)16-28-12-10-20(11-13-28)24-18-29(17-21-5-4-14-33-21)25-7-3-2-6-22(24)25/h2-9,14-15,18,20H,10-13,16-17H2,1H3,(H,30,31)
PubChem CID	10226501
ChEMBL	CHEMBL376202
IUPHAR	N/A
BindingDB	50156872
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
426536	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
426537	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
426535	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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