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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL223025
Molecular formula	C25H30N2O4
IUPAC name	2-methoxy-5-[[4-[1-(2-methoxyethyl)indol-3-yl]piperidin-1-yl]methyl]benzoic acid
Molecular weight	422.525
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.1
Synonyms	YNSYFJYJHVDOEP-UHFFFAOYSA-N 2-methoxy-5-{4-[1-(2-methoxyethyl)-1H-indol-3-yl]piperidin-1-ylmethyl}-benzoic acid BDBM50156896 SCHEMBL4051105 2-methoxy-5-{4-[1-(2-methoxyethyl)-1H-indol-3-yl]piperidin-1-ylmethyl}benzoic acid
Inchi Key	YNSYFJYJHVDOEP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30N2O4/c1-30-14-13-27-17-22(20-5-3-4-6-23(20)27)19-9-11-26(12-10-19)16-18-7-8-24(31-2)21(15-18)25(28)29/h3-8,15,17,19H,9-14,16H2,1-2H3,(H,28,29)
PubChem CID	9979651
ChEMBL	CHEMBL223025
IUPHAR	N/A
BindingDB	50156896
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
414872	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
414873	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
414871	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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