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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL15746097
Molecular formula	C22H25ClN2O3
IUPAC name	2-[(2R)-2-[(3-chlorophenoxy)methyl]morpholin-4-yl]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone
Molecular weight	400.903
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.8
Synonyms	US9079895, 65 BDBM186963
Inchi Key	XRYWJXIFEBMFIK-OTOKDRCRSA-N
Inchi ID	InChI=1S/C22H25ClN2O3/c1-16-11-17-5-2-3-8-21(17)25(16)22(26)14-24-9-10-27-20(13-24)15-28-19-7-4-6-18(23)12-19/h2-8,12,16,20H,9-11,13-15H2,1H3/t16?,20-/m1/s1
PubChem CID	90181065
ChEMBL	N/A
IUPHAR	N/A
BindingDB	186963
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
569710	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
569709	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
569711	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
569712	Alpha-1D adrenergic receptor	P97714	Adra1d	Mus musculus (Mouse)	562

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