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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1775171
Molecular formula	C21H25N5O5S
IUPAC name	propan-2-yl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxypiperidine-1-carboxylate
Molecular weight	459.521
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	2.6
Synonyms	SCHEMBL388759 BDBM50343449 isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate
Inchi Key	WMCWRFZUFUHFRB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H25N5O5S/c1-14(2)30-21(27)25-10-8-16(9-11-25)31-20-18-12-24-26(19(18)22-13-23-20)15-4-6-17(7-5-15)32(3,28)29/h4-7,12-14,16H,8-11H2,1-3H3
PubChem CID	11224944
ChEMBL	CHEMBL1775171
IUPHAR	N/A
BindingDB	50343449
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
376807	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
376808	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468

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