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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355959
Molecular formula	C32H35F2N3O2S
IUPAC name	ethyl 6-[2-ethyl-6-fluoro-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]indol-1-yl]pyridine-3-carboxylate
Molecular weight	563.708
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	7.3
Synonyms	BDBM50041197
Inchi Key	WCDMZYLZUNFULY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H35F2N3O2S/c1-3-28-31(22-14-17-36(18-15-22)16-5-19-40-26-10-7-24(33)8-11-26)27-12-9-25(34)20-29(27)37(28)30-13-6-23(21-35-30)32(38)39-4-2/h6-13,20-22H,3-5,14-19H2,1-2H3
PubChem CID	25024849
ChEMBL	CHEMBL3355959
IUPHAR	N/A
BindingDB	50041197
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
456387	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
456388	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
456389	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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