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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1773282
Molecular formula	C22H27N5O4S2
IUPAC name	tert-butyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanylpiperidine-1-carboxylate
Molecular weight	489.609
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.4
Synonyms	142920-EP2292620A2 TVVRUELYQUKMOC-UHFFFAOYSA-N BDBM50343452 142920-EP2287165A2 SCHEMBL389864 4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylsulfanyl]-piperidine-1-carboxylic acid tert-butyl ester 142920-EP2287166A2 tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylthio)piperidine-1-carboxylate [ Show all ]
Inchi Key	TVVRUELYQUKMOC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27N5O4S2/c1-22(2,3)31-21(28)26-11-9-16(10-12-26)32-20-18-13-25-27(19(18)23-14-24-20)15-5-7-17(8-6-15)33(4,29)30/h5-8,13-14,16H,9-12H2,1-4H3
PubChem CID	21897897
ChEMBL	CHEMBL1773282
IUPHAR	N/A
BindingDB	50343452
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
328719	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468
328720	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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