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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2153581
Molecular formula	C23H18F4N4O2
IUPAC name	N-[[3-[4-fluoro-3-(trifluoromethyl)phenyl]-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Molecular weight	458.417
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	4.0
Synonyms	GTPL5514 BDBM50393143 compound 5g [PMID: 21571530] N-[[3-[4-fluoro-3-(trifluoromethyl)phenyl]-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide D02FGK
Inchi Key	SWKGPCNQBPGWNX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H18F4N4O2/c24-19-9-7-15(11-18(19)23(25,26)27)20-12-17(33-31-20)13-29-21(32)5-1-4-16-8-6-14-3-2-10-28-22(14)30-16/h2-3,6-12H,1,4-5,13H2,(H,29,32)
PubChem CID	53358901
ChEMBL	CHEMBL2153581
IUPHAR	5514
BindingDB	50393143
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
324964	2-oxoglutarate receptor 1	Q96P68	OXGR1	Homo sapiens (Human)	337
324963	Succinate receptor 1	Q9BXA5	SUCNR1	Homo sapiens (Human)	334

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