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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15837
Molecular formula	C29H39FN6O2
IUPAC name	4-[4-(5-fluoro-1H-indol-3-yl)butyl]-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]piperazine-1-carboxamide
Molecular weight	522.669
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.7
Synonyms	N-[3-(4-Methylpiperazino)-4-methoxyphenyl]-4-[4-(5-fluoro-1H-indole-3-yl)butyl]piperazine-1-carboxamide 4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide BDBM50086101
Inchi Key	RXGJIWBUJGUKEZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H39FN6O2/c1-33-11-15-35(16-12-33)27-20-24(7-9-28(27)38-2)32-29(37)36-17-13-34(14-18-36)10-4-3-5-22-21-31-26-8-6-23(30)19-25(22)26/h6-9,19-21,31H,3-5,10-18H2,1-2H3,(H,32,37)
PubChem CID	10530035
ChEMBL	CHEMBL15837
IUPHAR	N/A
BindingDB	50086101
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
307352	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
307351	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
307353	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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