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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1773291
Molecular formula	C21H26N6O5S
IUPAC name	tert-butyl 4-[3-(4-methylsulfonylphenyl)triazolo[4,5-d]pyrimidin-7-yl]oxypiperidine-1-carboxylate
Molecular weight	474.536
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	2.4
Synonyms	143119-EP2292620A2 BDBM50343454 143119-EP2287165A2 SCHEMBL391340 4-[3-(4-Methanesulfonyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yloxy]-piperidine-1-carboxylic acid tert-butyl ester 143119-EP2287166A2 tert-butyl 4-(3-(4-(methylsulfonyl)phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yloxy)piperidine-1-carboxylate [ Show all ]
Inchi Key	RNXQXVJILIUHTG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26N6O5S/c1-21(2,3)32-20(28)26-11-9-15(10-12-26)31-19-17-18(22-13-23-19)27(25-24-17)14-5-7-16(8-6-14)33(4,29)30/h5-8,13,15H,9-12H2,1-4H3
PubChem CID	11465648
ChEMBL	CHEMBL1773291
IUPHAR	N/A
BindingDB	50343454
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
300882	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
300883	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468

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