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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL515397
Molecular formula	C27H32N2O5S
IUPAC name	4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-N-methylsulfonyl-2-propan-2-yloxybenzamide
Molecular weight	496.622
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	3.8
Synonyms	BDBM50277476 4''-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-3-isopropoxy-N-(methylsulfonyl)biphenyl-4-carboxamide Hydrochloride CHEMBL1187691
Inchi Key	RJTZTNJDJLXFEL-VWLOTQADSA-N
Inchi ID	InChI=1S/C27H32N2O5S/c1-19(2)34-26-17-23(13-14-24(26)27(31)29-35(3,32)33)21-11-9-20(10-12-21)15-16-28-18-25(30)22-7-5-4-6-8-22/h4-14,17,19,25,28,30H,15-16,18H2,1-3H3,(H,29,31)/t25-/m0/s1
PubChem CID	42639133
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50277476
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
297944	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
297943	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405
297945	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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