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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3963122
Molecular formula	C20H24ClN3O2
IUPAC name	(2S)-2-[(5-chloropyridin-3-yl)oxymethyl]-4-[2-(2,3-dihydroindol-1-yl)ethyl]morpholine
Molecular weight	373.881
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.0
Synonyms	SCHEMBL14149861 US9079895, 27s BDBM186942 QURJBQQAYVMKHZ-IBGZPJMESA-N (S)-2-(((5-Chloropyridin-3-yl)oxy)methyl)-4-(2-(indolin-1-yl)ethyl)morpholine
Inchi Key	QURJBQQAYVMKHZ-IBGZPJMESA-N
Inchi ID	InChI=1S/C20H24ClN3O2/c21-17-11-18(13-22-12-17)26-15-19-14-23(9-10-25-19)7-8-24-6-5-16-3-1-2-4-20(16)24/h1-4,11-13,19H,5-10,14-15H2/t19-/m0/s1
PubChem CID	71086428
ChEMBL	CHEMBL3963122
IUPHAR	N/A
BindingDB	186942
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
543762	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
543761	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
543760	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444
543759	D(4) dopamine receptor	P51436	Drd4	Mus musculus (Mouse)	387

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