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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(4) dopamine receptor
Species	Mus musculus (Mouse)
Gene	Drd4
Synonym	d(2C) dopamine receptor D4 receptor D4R Dopamine D4 receptor dopamine receptor 4
Disease	N/A for non-human GPCRs
Length	387
Amino acid sequence	MGNSSATEDGGLLAGRGPESLGTGAGLGGAGAAALVGGVLLIGLVLAGNSLVCVSVASERTLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVASPVVCGLNDVPGRDPAVCCLENRDYVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPFFPDCPPPLPSLRTSPSDSSRPESELSQRPCSPGCLLADAALPQPPEPSSRRRRGAKITGRERKAMRVLPVVVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
UniProt	P51436
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2574
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3963122
Molecular formula	C20H24ClN3O2
IUPAC name	(2S)-2-[(5-chloropyridin-3-yl)oxymethyl]-4-[2-(2,3-dihydroindol-1-yl)ethyl]morpholine
Molecular weight	373.881
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.0
Synonyms	SCHEMBL14149861 US9079895, 27s BDBM186942 QURJBQQAYVMKHZ-IBGZPJMESA-N (S)-2-(((5-Chloropyridin-3-yl)oxy)methyl)-4-(2-(indolin-1-yl)ethyl)morpholine
Inchi Key	QURJBQQAYVMKHZ-IBGZPJMESA-N
Inchi ID	InChI=1S/C20H24ClN3O2/c21-17-11-18(13-22-12-17)26-15-19-14-23(9-10-25-19)7-8-24-6-5-16-3-1-2-4-20(16)24/h1-4,11-13,19H,5-10,14-15H2/t19-/m0/s1
PubChem CID	71086428
ChEMBL	CHEMBL3963122
IUPHAR	N/A
BindingDB	186942
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	90.0 nM	, None	BindingDB,ChEMBL
Ki	3618.0 nM	None	ChEMBL

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