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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	Framycetin
Molecular formula	C23H46N6O13
IUPAC name	(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
Molecular weight	614.65
Hydrogen bond acceptor	19
Hydrogen bond donor	13
XlogP	-9.0
Synonyms	LS-96095 30384-EP2305698A2 NCGC00179612-01 AB00443887-03 Neomas Antibiotic 956 Neomycin B sulfate BRN 0101621 Neomycinum CHEBI:7508 SCHEMBL3279 UNII-4BOC774388 Fradiomycin (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]oxy-3-hydroxy-cyclohexoxy]tetrahyd Framycetin [INN:BAN:DCF] 1393-86-8 HMS2089P15 30384-EP2292620A2 30384-EP2298776A1 Myacyne 4BOC774388 Neo-Rx Actiline Neomicina [DCIT] BDBM19 Neomycin sulphate C01737 NMY D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1.->3)-O-.beta.-D-ribofuranosyl-(1->5)]-O-[2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy Soframycin (TN) EINECS 204-292-2 Framicetina (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3S,4R,5S)-5-{[(1R,2R,3S,5R,6S)-3,5-diamino-2-{[(2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-6-hydroxycyclohexyl]oxy}-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol Framycetinum 30384-EP2272825A2 J-004060 VONAMYCIN lohexyloxy)(3S,2R,4R,5R,6R)-5-amino- 2-(aminomethyl)-2H-3,4,5,6-tetrahydropyran-3,4-diol 30384-EP2305696A2 Mycifradin (TN) Neobrettin AN-5730 NEOMYCIN AND POLYMYXIN B SULFATES BPBio1_000326 Neomycine Caswell No. 595 Prestwick3_000158 D05JNI ST075177 Enterfram Framycetin (INN) 11025-81-3 Fraquinol 30384-EP2287165A2 MolPort-003-938-736 30384-EP2311464A1 Neo-Fradin AC1L1QVH Neomcin Antibiotic produced by Streptomyces decaris. Neomycin B Neomycin solution BSPBio_000296 Neomycinum [INN-Latin] CHEMBL184618 Sofra-Tulle (TN) DB00452 UNII-I16QD7X297 component PGBHMTALBVVCIT-VCIWKGPPSA-N Fradiomycin B (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol Framycetine 1404-04-2 HSDB 3242 30384-EP2295401A2 30384-EP2305662A1 Mycerin 6-(2-{(4S,2R,3R,5R)-4-[(5S,6S,2R,3R,4R)-3-amino-6-(aminomethyl)-4,5-dihydroxy( 2H-3,4,5,6-tetrahydropyran-2-yloxy)]-3-hydroxy-5-(hydroxymethyl)oxolan-2-yloxy }(3S,6S,1R,2R,4R)-4,6-diamino-3-hydroxycyc Neo-Tab (TN) AKOS024284361 Neomin BDG-(1-4)CYY-(5-1)RIB-(3-1)IDG Neomycin trisulfate salt hydrate C23H46N6O13 PGBHMTALBVVCIT-VCIWKGPPSA-N D-Streptamine, O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-beta-D-ribofuranosyl-(1-5))-2-deoxy- Soframycin Ophthalmic EINECS 215-766-3 Framicetina [INN-Spanish] 11004-65-2 Framycetinum [INN-Latin] 30384-EP2272838A1 Jernadex Vonamycin powder V LS-96091 30384-EP2305697A2 Myciguent AB00443887 Neolate Antibiotic 10676 NEOMYCIN B BRD-K71013094-065-01-2 Neomycine [INN-French] CCRIS 5462 SC-83646 D0RD0N Tuttomycin EPA Pesticide Chemical Code 006303 (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside Framycetin sulfate 119-04-0 GTPL709 30384-EP2287166A2 Myacine 4-18-00-07476 (Beilstein Handbook Reference) Neo-fradin (TN) Actilin Neomicina Antibiotique NEOMYCIN SULFATE Bycomycin Nivemycin CS-6390 Soframycin DTXSID2023359 Fradiomycinum (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}oxane-3,4-diol Framycetine [INN-French] 1405-10-3 (sulfate (salt)) HY-17624 30384-EP2295402A2 USAF CB-19 30384-EP2305695A2 Mycifradin 6-(2-{(4S,2R,3R,5R)-4-[(5S,6S,2R,3R,4R)-3-amino-6-(aminomethyl)-4,5-dihydroxy( 2H-3,4,5,6-tetrahydropyran-2-yloxy)]-3-hydroxy-5-(hydroxymethyl)oxolan-2-yloxy }(3S,6S,1R,2R,4R)-4,6-diamino-3-hydroxycyclohexyloxy)(3S,2R,4R,5R,6R)-5-amino- 2-(aminomethyl)-2H Neobiotic AN-49153 neomycin BDG-(1-4)NEB-(5-1)RIB-(3-1)NED Neomycin [INN:BAN] C25H50N6O13 PIMAVECORT D05140 Soframycine Endomixin 11013-50-6 Framygen 30384-EP2277898A2 KDR Kinase Inhibitor, 3 ZINC71928291 [ Show all ]
Inchi Key	PGBHMTALBVVCIT-VCIWKGPPSA-N
Inchi ID	InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
PubChem CID	8378
ChEMBL	N/A
IUPHAR	709
BindingDB	N/A
DrugBank	DB00452
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
258900	C-X-C chemokine receptor type 4	P61073	CXCR4	Homo sapiens (Human)	352
554559	Extracellular calcium-sensing receptor	P48442	Casr	Rattus norvegicus (Rat)	1079

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