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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15808
Molecular formula	C24H28FN5O2
IUPAC name	8-fluoro-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carboxamide
Molecular weight	437.519
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.8
Synonyms	BDBM50086103 N-[3-(4-Methylpiperazino)-4-methoxyphenyl]-2,3,4,5-tetrahydro-8-fluoro-1H-pyrido[4,3-b]indole-2-carboxamide 8-Fluoro-1,3,4,5-tetrahydro-pyrido[4,3-b]indole-2-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Inchi Key	OKAPXVXSORGNAI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H28FN5O2/c1-28-9-11-29(12-10-28)22-14-17(4-6-23(22)32-2)26-24(31)30-8-7-21-19(15-30)18-13-16(25)3-5-20(18)27-21/h3-6,13-14,27H,7-12,15H2,1-2H3,(H,26,31)
PubChem CID	10646633
ChEMBL	CHEMBL15808
IUPHAR	N/A
BindingDB	50086103
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
243312	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
243311	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
243310	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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