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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2164242
Molecular formula	C27H30FNO5S
IUPAC name	3-[2-fluoro-4-[[3-[2-methyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methylamino]phenyl]propanoic acid
Molecular weight	499.597
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	5.0
Synonyms	GTPL9149 3-{2-fluoro-4-[({3-[4-(3-methanesulfonylpropoxy)-2-methylphenyl]phenyl}methyl)amino]phenyl}propanoic acid TUG-905 agonist 13 [PMID: 22724451] BDBM50395072
Inchi Key	ODIHLEYTPVYAPY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H30FNO5S/c1-19-15-24(34-13-4-14-35(2,32)33)10-11-25(19)22-6-3-5-20(16-22)18-29-23-9-7-21(26(28)17-23)8-12-27(30)31/h3,5-7,9-11,15-17,29H,4,8,12-14,18H2,1-2H3,(H,30,31)
PubChem CID	60195125
ChEMBL	CHEMBL2164242
IUPHAR	9149
BindingDB	50395072
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
238426	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300
238427	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300
238425	Free fatty acid receptor 4	Q5NUL3	FFAR4	Homo sapiens (Human)	377

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