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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1775172
Molecular formula	C22H27N5O5S
IUPAC name	butyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxypiperidine-1-carboxylate
Molecular weight	473.548
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.1
Synonyms	4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy]-piperidine-1-carboxylic acid butyl ester butyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate NRJQNFPQCLDLSO-UHFFFAOYSA-N SCHEMBL389883 BDBM50343455
Inchi Key	NRJQNFPQCLDLSO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27N5O5S/c1-3-4-13-31-22(28)26-11-9-17(10-12-26)32-21-19-14-25-27(20(19)23-15-24-21)16-5-7-18(8-6-16)33(2,29)30/h5-8,14-15,17H,3-4,9-13H2,1-2H3
PubChem CID	54586882
ChEMBL	CHEMBL1775172
IUPHAR	N/A
BindingDB	50343455
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
230197	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
230198	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468

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