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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL61964
Molecular formula	C13H15ClN2O4
IUPAC name	(2R,4R)-4-amino-1-[(4-chlorophenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Molecular weight	298.723
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.9
Synonyms	BDBM50071157 SCHEMBL8973457 (2R,4R)-4-Amino-1-(4-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid
Inchi Key	MRJISECQFHIMGI-ZWNOBZJWSA-N
Inchi ID	InChI=1S/C13H15ClN2O4/c14-9-3-1-8(2-4-9)6-16-7-13(15,12(19)20)5-10(16)11(17)18/h1-4,10H,5-7,15H2,(H,17,18)(H,19,20)/t10-,13-/m1/s1
PubChem CID	44302932
ChEMBL	CHEMBL61964
IUPHAR	N/A
BindingDB	50071157
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
212454	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
212453	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
212451	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
212452	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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