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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL280000
Molecular formula	C28H37N5O2
IUPAC name	4-[2-(1H-indol-3-yl)ethyl]-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]piperidine-1-carboxamide
Molecular weight	475.637
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.4
Synonyms	BDBM50086104 N-[3-(4-Methylpiperazino)-4-methoxyphenyl]-4-[2-(1H-indole-3-yl)ethyl]piperidine-1-carboxamide 4-[2-(1H-Indol-3-yl)-ethyl]-piperidine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide SCHEMBL6347264
Inchi Key	MLYDWVQYHWPBIQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H37N5O2/c1-31-15-17-32(18-16-31)26-19-23(9-10-27(26)35-2)30-28(34)33-13-11-21(12-14-33)7-8-22-20-29-25-6-4-3-5-24(22)25/h3-6,9-10,19-21,29H,7-8,11-18H2,1-2H3,(H,30,34)
PubChem CID	10814424
ChEMBL	CHEMBL280000
IUPHAR	N/A
BindingDB	50086104
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
208757	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
208756	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
208755	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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