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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL325140
Molecular formula	C21H21NO5
IUPAC name	(1S,2S,3R)-2-[amino(carboxy)methyl]-3-[2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid
Molecular weight	367.401
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	0.6
Synonyms	(1S,2S,3R)-2-(Amino-carboxy-methyl)-3-[2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid BDBM50107108
Inchi Key	MBCWMEYAVJTLQS-QPZJVUEUSA-N
Inchi ID	InChI=1S/C21H21NO5/c22-19(21(25)26)17-14(18(17)20(23)24)10-9-11-12-5-1-3-7-15(12)27-16-8-4-2-6-13(11)16/h1-8,11,14,17-19H,9-10,22H2,(H,23,24)(H,25,26)/t14-,17+,18+,19?/m1/s1
PubChem CID	9885546
ChEMBL	CHEMBL325140
IUPHAR	N/A
BindingDB	50089894, 50107108
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
201225	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
201226	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
201227	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879

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