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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2036309
Molecular formula	C25H30N2O4S
IUPAC name	4-[2-[(2R)-2-[(E,3S)-3-hydroxy-4-(3-pyridin-2-ylphenyl)but-1-enyl]-5-oxopyrrolidin-1-yl]ethylsulfanyl]butanoic acid
Molecular weight	454.585
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.5
Synonyms	BDBM50385119 SCHEMBL10210637
Inchi Key	KPLWANAFZOCKMN-JEUBMUGFSA-N
Inchi ID	InChI=1S/C25H30N2O4S/c28-22(18-19-5-3-6-20(17-19)23-7-1-2-13-26-23)11-9-21-10-12-24(29)27(21)14-16-32-15-4-8-25(30)31/h1-3,5-7,9,11,13,17,21-22,28H,4,8,10,12,14-16,18H2,(H,30,31)/b11-9+/t21-,22+/m0/s1
PubChem CID	57893916
ChEMBL	CHEMBL2036309
IUPHAR	N/A
BindingDB	50385119
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
174943	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
174944	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
174945	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
174946	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
174947	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488

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