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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1778152
Molecular formula	C21H25F3N4O4S
IUPAC name	(1S,5S)-3-[5-methyl-6-(2-methylpyridin-3-yl)oxypyrimidin-4-yl]oxy-8-(3,3,3-trifluoropropylsulfonyl)-8-azabicyclo[3.2.1]octane
Molecular weight	486.51
Hydrogen bond acceptor	11
Hydrogen bond donor	0
XlogP	4.0
Synonyms	SCHEMBL12275425 BDBM50344497 (1S,5S)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyrimidin-4-yloxy)-8-(3,3,3-trifluoropropylsulfonyl)-8-azabicyclo[3.2.1]octane
Inchi Key	JEQHGHRMOQYJDU-HOTGVXAUSA-N
Inchi ID	InChI=1S/C21H25F3N4O4S/c1-13-19(26-12-27-20(13)32-18-4-3-8-25-14(18)2)31-17-10-15-5-6-16(11-17)28(15)33(29,30)9-7-21(22,23)24/h3-4,8,12,15-17H,5-7,9-11H2,1-2H3/t15-,16-/m0/s1
PubChem CID	54583651
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50344497
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
149083	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
149084	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335

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