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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1830711
Molecular formula	C13H12N6S
IUPAC name	N-pyrimidin-2-yl-5-thia-3,11,12-triazatricyclo[8.3.0.02,6]trideca-1(10),2(6),3,12-tetraen-4-amine
Molecular weight	284.341
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.1
Synonyms	BDBM50353291 SCHEMBL370495
Inchi Key	HYJWPTWQMAYKAM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)
PubChem CID	46836713
ChEMBL	CHEMBL1830711
IUPHAR	N/A
BindingDB	50353291
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
127109	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
127111	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
127113	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
127114	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
127112	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
127110	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915

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