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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17418658
Molecular formula	C27H27FN2O4
IUPAC name	(3S)-3-cyclopropyl-3-[3-[[6-cyclopropyl-5-(2-fluoro-5-methoxyphenyl)pyrazin-2-yl]methoxy]phenyl]propanoic acid
Molecular weight	462.521
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.3
Synonyms	BDBM168181 US9688642, 39 (3S)-3-Cyclopropyl-3-(3-((6-cyclopropyl-5-(2-fluoro-5-methoxyphenyl)pyrazin-2-yl)methoxy)phenyl)propanoic acid HWZPREYQYNXWKH-QFIPXVFZSA-N
Inchi Key	HWZPREYQYNXWKH-QFIPXVFZSA-N
Inchi ID	InChI=1S/C27H27FN2O4/c1-33-20-9-10-24(28)23(12-20)27-26(17-7-8-17)30-19(14-29-27)15-34-21-4-2-3-18(11-21)22(13-25(31)32)16-5-6-16/h2-4,9-12,14,16-17,22H,5-8,13,15H2,1H3,(H,31,32)/t22-/m0/s1
PubChem CID	118645455
ChEMBL	N/A
IUPHAR	N/A
BindingDB	168181
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
561222	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300
561223	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300

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