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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15909
Molecular formula	C29H36FN5O2
IUPAC name	1-[2-[4-(6-fluoro-1H-indol-3-yl)piperidin-1-yl]ethyl]-3-(1'-methylspiro[2H-1-benzofuran-3,4'-piperidine]-5-yl)urea
Molecular weight	505.638
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.8
Synonyms	1-[1'-Methylspiro[benzofuran-3(2H),4'-piperidine]-5-yl]-3-[2-[4-(6-fluoro-1H-indole-3-yl)piperidino]ethyl]urea BDBM50086117 1-{2-[4-(6-fluoro-1H-indol-3-yl)piperidin-1yl]ethyl}-[2,3-Dihydro-1''-methylspiro(benzofuran-3,4''-piperidine)]-amide
Inchi Key	HCDXKCGDMXPSKS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H36FN5O2/c1-34-13-8-29(9-14-34)19-37-27-5-3-22(17-25(27)29)33-28(36)31-10-15-35-11-6-20(7-12-35)24-18-32-26-16-21(30)2-4-23(24)26/h2-5,16-18,20,32H,6-15,19H2,1H3,(H2,31,33,36)
PubChem CID	10625376
ChEMBL	CHEMBL15909
IUPHAR	N/A
BindingDB	50086117
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
111189	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
111188	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
111190	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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