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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000778974
Molecular formula	C17H13F3N2O3
IUPAC name	4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-3-yl]benzene-1,3-diol
Molecular weight	350.297
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	3.7
Synonyms	4-(4-(4-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-3-yl)benzene-1,3-diol AC1NWN1Y EU-0039436 MLS000778974-02 (4E)-3-hydroxy-4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-3-pyrazolin-3-ylidene]cyclohexa-2,5-dien-1-one 4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-3-yl]benzene-1,3-diol AKOS002228672 HMS2743K09 SMR000415669 3-hydroxy-4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one AB00114303-01 CHEMBL1460039 MLS-0392664.0001 ZINC85382232 (4E)-3-hydroxy-4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,5-dienone 4-[4-(4-Methoxy-phenyl)-5-trifluoromethyl-1H-pyrazol-3-yl]-benzene-1,3-diol AC1O9FFO F0758-0081 MolPort-000-811-251 (4E)-4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]-3-oxidanyl-cyclohexa-2,5-dien-1-one 4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)pyrazol-3-yl]benzene-1,3-diol BDBM61556 IFLab1_003427 ST50471194 394237-70-8 AC1NUKIQ cid_5732140 (4E)-3-hydroxy-4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one 4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-3-yl]-1,3-benzenediol AC1Q4A45 HMS1421L17 MolPort-001-818-970 (4Z)-3-hydroxy-4-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one MCULE-2287753261 STK829623 [ Show all ]
Inchi Key	FVVBPMRBFOQCQK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H13F3N2O3/c1-25-11-5-2-9(3-6-11)14-15(21-22-16(14)17(18,19)20)12-7-4-10(23)8-13(12)24/h2-8,23-24H,1H3,(H,21,22)
PubChem CID	1322439
ChEMBL	CHEMBL1460039
IUPHAR	N/A
BindingDB	61556
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
560009	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
560008	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360
560010	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
560011	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319
560012	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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