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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS-0437175.0001
Molecular formula	C20H18N4
IUPAC name	7-methyl-2,4-bis(4-methylphenyl)pyrazolo[3,4-d]pyridazine
Molecular weight	314.392
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.9
Synonyms	MCULE-9925304846 ZINC36649130 CHEMBL1707517 7-methyl-2,4-bis(4-methylphenyl)pyrazolo[3,4-d]pyridazine BDBM76071 cid_45917986 7-methyl-2,4-bis(p-tolyl)pyrazolo[3,4-d]pyridazine MolPort-009-015-009 [ Show all ]
Inchi Key	FTYRPHUIBDQVCC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18N4/c1-13-4-8-16(9-5-13)20-18-12-24(17-10-6-14(2)7-11-17)23-19(18)15(3)21-22-20/h4-12H,1-3H3
PubChem CID	45917986
ChEMBL	CHEMBL1707517
IUPHAR	N/A
BindingDB	76071
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
87245	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
87247	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360
87246	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
87248	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319

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