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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL221678
Molecular formula	C25H29FN2O4
IUPAC name	5-[[4-[6-fluoro-1-(2-methoxyethyl)indol-3-yl]piperidin-1-yl]methyl]-2-methoxybenzoic acid
Molecular weight	440.515
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.2
Synonyms	SCHEMBL4051375 5-{4-[6-fluoro-1-(2-methoxyethyl)-1H-indol-3-yl]piperidin-1-ylmethyl}-2-methoxybenzoic acid BDBM50156885
Inchi Key	FLBZQKOWWVQHOV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29FN2O4/c1-31-12-11-28-16-22(20-5-4-19(26)14-23(20)28)18-7-9-27(10-8-18)15-17-3-6-24(32-2)21(13-17)25(29)30/h3-6,13-14,16,18H,7-12,15H2,1-2H3,(H,29,30)
PubChem CID	10003369
ChEMBL	CHEMBL221678
IUPHAR	N/A
BindingDB	50156885
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
81062	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
81064	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
81063	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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