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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17418795
Molecular formula	C27H28FN3O5
IUPAC name	(3S)-3-cyclopropyl-3-[3-[[6-(cyclopropylmethoxy)-5-(5-fluoro-2-methoxypyridin-4-yl)pyrazin-2-yl]methoxy]phenyl]propanoic acid
Molecular weight	493.535
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	4.0
Synonyms	BDBM168195 US9688642, 48 (3S)-3-Cyclopropyl-3-(3-((6-(cyclopropylmethoxy)-5-(5-fluoro-2-methoxypyridin-4-yl)pyrazin-2-yl)methoxy)phenyl)propanoic acid FIXVGIZULFZMHK-NRFANRHFSA-N
Inchi Key	FIXVGIZULFZMHK-NRFANRHFSA-N
Inchi ID	InChI=1S/C27H28FN3O5/c1-34-24-10-22(23(28)13-29-24)26-27(36-14-16-5-6-16)31-19(12-30-26)15-35-20-4-2-3-18(9-20)21(11-25(32)33)17-7-8-17/h2-4,9-10,12-13,16-17,21H,5-8,11,14-15H2,1H3,(H,32,33)/t21-/m0/s1
PubChem CID	118645573
ChEMBL	N/A
IUPHAR	N/A
BindingDB	168195
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
559766	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300
559767	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300

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