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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL356972
Molecular formula	C22H25N3O4S
IUPAC name	N-(4,6-dimethoxypyrimidin-2-yl)-2-[4-(2-methylpropyl)phenyl]benzenesulfonamide
Molecular weight	427.519
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.9
Synonyms	BDBM50068749 N-(4,6-Dimethoxypyrimidine-2-yl)-4'-(2-methylpropyl)-1,1'-biphenyl-2-sulfonamide 4''-Isobutyl-biphenyl-2-sulfonic acid (4,6-dimethoxy-pyrimidin-2-yl)-amide
Inchi Key	DMDOZLAWJSQBRQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25N3O4S/c1-15(2)13-16-9-11-17(12-10-16)18-7-5-6-8-19(18)30(26,27)25-22-23-20(28-3)14-21(24-22)29-4/h5-12,14-15H,13H2,1-4H3,(H,23,24,25)
PubChem CID	10526510
ChEMBL	CHEMBL356972
IUPHAR	N/A
BindingDB	50068749
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
63580	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
63581	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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