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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL63289
Molecular formula	C16H18N4O2S
IUPAC name	ethyl 4-(3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-8-yl)piperazine-1-carboxylate
Molecular weight	330.406
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.4
Synonyms	SCHEMBL7295524 BDBM50407761
Inchi Key	DLRDSROWZPGGDS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H18N4O2S/c1-2-22-16(21)19-9-7-18(8-10-19)14-13-4-3-6-20(13)15-12(17-14)5-11-23-15/h3-6,11H,2,7-10H2,1H3
PubChem CID	10687868
ChEMBL	CHEMBL63289
IUPHAR	N/A
BindingDB	50407761
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
63270	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
63272	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
63269	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
63271	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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