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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL421365
Molecular formula	C23H22O4S
IUPAC name	4-(2-methylphenyl)-5-oxo-5-[3-(thiophen-3-ylmethoxy)phenyl]pentanoic acid
Molecular weight	394.485
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.6
Synonyms	gamma-[3-(3-Thienylmethoxy)benzoyl]-2-methylbenzenebutyric acid 5-Oxo-5-[3-(thiophen-3-ylmethoxy)-phenyl]-4-o-tolyl-pentanoic acid SCHEMBL7908362 BDBM50065514
Inchi Key	DHSRZCIYOWGXNT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22O4S/c1-16-5-2-3-8-20(16)21(9-10-22(24)25)23(26)18-6-4-7-19(13-18)27-14-17-11-12-28-15-17/h2-8,11-13,15,21H,9-10,14H2,1H3,(H,24,25)
PubChem CID	15304942
ChEMBL	CHEMBL421365
IUPHAR	N/A
BindingDB	50065514
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
60308	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
60307	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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