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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1775174
Molecular formula	C23H27N5O5S
IUPAC name	cyclopentyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxypiperidine-1-carboxylate
Molecular weight	485.559
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.1
Synonyms	cyclopentyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate 4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy]-piperidine-1-carboxylic acid cyclopentyl ester 144269-EP2287166A2 SCHEMBL390855 144269-EP2292620A2 BDBM50343459 [ Show all ]
Inchi Key	DHRDKLVPQRXOQS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H27N5O5S/c1-34(30,31)19-8-6-16(7-9-19)28-21-20(14-26-28)22(25-15-24-21)32-18-10-12-27(13-11-18)23(29)33-17-4-2-3-5-17/h6-9,14-15,17-18H,2-5,10-13H2,1H3
PubChem CID	53630450
ChEMBL	CHEMBL1775174
IUPHAR	N/A
BindingDB	50343459
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
60259	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
60260	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468

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