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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1830707
Molecular formula	C14H13N5S
IUPAC name	N-pyridin-2-yl-5-thia-3,11,12-triazatricyclo[8.3.0.02,6]trideca-1(10),2(6),3,12-tetraen-4-amine
Molecular weight	283.353
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.8
Synonyms	D00NCL BDBM50353290 N-(pyridin-2-yl)-5-thia-3,11,12-triazatricyclo[8.3.0.0^{2,6}]trideca-1(13),2(6),3,10-tetraen-4-amine 1314140-00-5 compound 22a TC-N 22A GTPL6231 NCGC00371008-01 4,5,6,8-Tetrahydro-N-2-pyridinylpyrazolo[3',4':6,7]cyclohepta[1,2]thiazol-2-amine compound 22a [PMID: 21688779] ZINC72118775 AKOS024458120 MolPort-023-277-166 SCHEMBL369389 [ Show all ]
Inchi Key	DBISXWCOHGUFSF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)
PubChem CID	46836562
ChEMBL	CHEMBL1830707
IUPHAR	6231
BindingDB	50353290
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
55711	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
55706	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
55710	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
55707	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
55708	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
55709	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915

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