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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL549577
Molecular formula	C21H21NO3
IUPAC name	[(3R)-1-azabicyclo[2.2.2]octan-3-yl] 9H-xanthene-9-carboxylate
Molecular weight	335.403
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	[(3R)-1-azabicyclo[2.2.2]octan-3-yl] 9H-xanthene-9-carboxylate BDBM50296314 SCHEMBL7200244 9H-Xanthene-9-carboxylic acid [(1beta,4beta)-1-azabicyclo[2.2.2]octan-3alpha-yl] ester (3R)-1-Azabicyclo[2.2.2]oct-3-yl9H-xanthene-9-carboxylate ZINC534282 AC1LIVNS [ Show all ]
Inchi Key	DAIWBMZPSVQRCH-IBGZPJMESA-N
Inchi ID	InChI=1S/C21H21NO3/c23-21(25-19-13-22-11-9-14(19)10-12-22)20-15-5-1-3-7-17(15)24-18-8-4-2-6-16(18)20/h1-8,14,19-20H,9-13H2/t19-/m0/s1
PubChem CID	939077
ChEMBL	CHEMBL549577
IUPHAR	N/A
BindingDB	50296314
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
55055	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
55058	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
55054	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
55057	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
55056	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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